Pyridazines and derivatives
Medchemexpress LLC Zardaverine | 101975-10-4 | C12H10F2N2O3 | 1 ML
Zardaverine is an orally active and selective PDE3/4 inhibitor with potent bronchodilator activity. It selectively inhibits the proliferation of HCC cells, inducing apoptosis and cell cycle arrest (G0/G1 phase). Zardaverine demonstrates good antitumor potential and is effective in bronchial relaxation and reducing inflammation in asthma.
- Targets phosphodiesterase (PDE) and apoptosis
- Pathway: Metabolic enzyme/protease and apoptosis
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 2 years, -20°C for 1 year
- Soluble in DMSO (25 mg/mL)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (≥ 2.08 mg/mL)
- Soluble in 10% DMSO, 90% corn oil (≥ 2.08 mg/mL)
- IC₅₀ target: PDE3, PDE4
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 25 G
Phthalazine (Standard) is the analytical standard for Phthalazine, designed for research and analytical applications. It functions as a substrate for human aldehyde oxidase 1, which can lead to the generation of Reactive Oxygen Species (ROS) and subsequent inactivation of the enzyme. This product is an organic heterocyclic compound containing nitrogen. It has demonstrated antitumor activity in various cancers, including blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
- Analytical standard for various assays.
- Utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Exhibits antitumor activity against blood cancer, breast cancer, colon cancer, lung cancer, and renal cancer.
Aobchem 1-(5 6-Dichloro-3-pyridinyl)-2-methyl-1-propanone | 95% | CAS 1240248-34-3 | C9H9Cl2NO | 500mg
1-(5 6-Dichloro-3-pyridinyl)-2-methyl-1-propanone | 95% | CAS 1240248-34-3 | C9H9Cl2NO | 500mg
Aobchem N-(4-isopropylphenyl)pivalamide | 97% | CAS 448250-70-2 | C14H21NO | 1g
N-(4-isopropylphenyl)pivalamide | 97% | CAS 448250-70-2 | C14H21NO | 1g
Aobchem 1-(2-Bromo-5-isopropylphenyl)-2-methylpropan-1-one | 95% | C13H17BrO | 500mg
1-(2-Bromo-5-isopropylphenyl)-2-methylpropan-1-one | 95% | C13H17BrO | 500mg
Aobchem 2-Fluoro-1-(4-isopropylphenyl)ethanone | ≥95% | CAS 1076195-18-0 | C11H13FO | 1g
2-Fluoro-1-(4-isopropylphenyl)ethanone | ≥95% | CAS 1076195-18-0 | C11H13FO | 1g
Aobchem (4-Fluoro-3-isopropylphenyl)boronic acid | 95% | C9H12BFO2 | 1g
(4-Fluoro-3-isopropylphenyl)boronic acid | 95% | C9H12BFO2 | 1g
Aobchem 2-(3-Bromo-5-isopropylphenyl)propan-2-ol | 95% | CAS 1897312-20-7 | C12H17BrO | 1g
2-(3-Bromo-5-isopropylphenyl)propan-2-ol | 95% | CAS 1897312-20-7 | C12H17BrO | 1g
Aobchem (4-Chloro-2-isopropylphenyl)boronic acid | ≥97% | CAS 1395084-16-8 | C9H12BClO2 | 250mg
(4-Chloro-2-isopropylphenyl)boronic acid | ≥97% | CAS 1395084-16-8 | C9H12BClO2 | 250mg
Aobchem (2-Ethoxy-5-isopropylphenyl)trimethylsilane | 95% | C14H24OSi | 1g
(2-Ethoxy-5-isopropylphenyl)trimethylsilane | 95% | C14H24OSi | 1g
Aobchem (4-Ethoxy-3-isopropylphenyl)boronic acid | 97% | C11H17BO3 | 1g
(4-Ethoxy-3-isopropylphenyl)boronic acid | 97% | C11H17BO3 | 1g
Aobchem (4-Ethoxy-3-isopropylphenyl)boronic acid | 97% | C11H17BO3 | 500mg
(4-Ethoxy-3-isopropylphenyl)boronic acid | 97% | C11H17BO3 | 500mg
Aobchem 2-((3-Isopropylphenyl)thio)pyridine | 95% | C14H15NS | 250mg
2-((3-Isopropylphenyl)thio)pyridine | 95% | C14H15NS | 250mg
Aobchem 1-(4-Chloro-3-isopropylphenyl)-2-methylpropan-1-ol | 95% | C13H19ClO | 1g
1-(4-Chloro-3-isopropylphenyl)-2-methylpropan-1-ol | 95% | C13H19ClO | 1g
Aobchem (3-Fluoro-4-isopropylphenyl)trimethylsilane | 95% | C12H19FSi | 250mg
(3-Fluoro-4-isopropylphenyl)trimethylsilane | 95% | C12H19FSi | 250mg